An electrospun polydioxanone patch for the localisation of biological therapies during tendon repair.

Journal article

Rotator cuff tendon pathology is thought to account for 30-70 % of all shoulder pain. For cases that have failed conservative treatment, surgical re-attachment of the tendon to the bone with a non-absorbable suture is a common option. However, the failure rate of these repairs is high, estimated at up to 75 %. Studies have shown that in late disease stages the tendon itself is extremely degenerate, with reduced cell numbers and poor matrix organisation. Thus, it has been suggested that adding...

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Authors: Hakimi, O; Murphy, R; Stachewicz, U; Hislop, S; Carr, A

• Publication status: Published
• Journal: European cells and materials
• Volume: 24
• Pages: 344-357
• Publication date: 2012-01-01
• EISSN: 1473-2262
• ISSN: 1473-2262
• Language: English
• Keywords: Cell Proliferation; Tendons; Materials Testing; Wound Healing; Cell Line; Polydioxanone; Rotator Cuff; Cell Adhesion; Cell Movement; Humans