- Abstract:
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Purpose Minimal residual disease (MRD) and genetic abnormalities are important risk factors for outcome in acute lymphoblastic leukemia. Current risk algorithms dichotomize MRD data and do not assimilate genetics when assigning MRD risk, which reduces predictive accuracy. The aim of our study was to exploit the full power of MRD by examining it as a continuous variable and to integrate it with genetics. Patients and Methods We used a population-based cohort ... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
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(pdf, 1.5MB)
-
- Publisher copy:
- 10.1200/JCO.2017.74.0449
-
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- Publisher:
- American Society of Clinical Oncology Publisher's website
- Journal:
- Journal of Clinical Oncology Journal website
- Volume:
- 36
- Issue:
- 1
- Pages:
- 34-43
- Publication date:
- 2017-11-13
- Acceptance date:
- 2017-09-26
- DOI:
- EISSN:
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1527-7755
- ISSN:
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0732-183X
- Pubs id:
-
pubs:745909
- URN:
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uri:4a972813-f7b6-4f4f-8f55-5bc3c8c7dabd
- UUID:
-
uuid:4a972813-f7b6-4f4f-8f55-5bc3c8c7dabd
- Local pid:
- pubs:745909
- Paper number:
- 1
- Copyright holder:
- American Society of Clinical Oncology
- Copyright date:
- 2017
- Notes:
-
Copyright © 2017 by American Society of Clinical Oncology. Licensed under the Creative
Commons Attribution 4.0 License.
Journal article
Genotype-specific MRD interpretation improves stratification in paediatric acute lymphoblastic leukaemia
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