- Acyclic allylic monofluorides were prepared by electrophilic fluorination of branched (E)-allylsilanes with Selectfluor. These reactions proceeded with efficient transfer of chirality from the silylated to the fluorinated stereocentre. Upon double fluorination, an unsymmetrical ethyl syn-2.5-difluoroalk-3-enoic ester was prepared, the silyl group acting as an anti stereodirecting group for the two C-F bond forming events.
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Citation: Sawicki, M. et al. (2007). 'Single and double stereoselective fluorination of (E)-allylsilanes', Beilstein Journal of Organic Chemistry, 3, 34. [Available at http://www.beilstein-journals.org/bjoc/home/home.htm]. © 2007 Sawicki et al; licensee Beilstein-Institut. This is an Open Access article under the terms of the
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