Molecules labelled with the unnatural isotope fluorine-18 are used for positron emission tomography. Currently, this molecular imaging technology is not exploited at its full potential because many (18)F-labelled probes are inaccessible or notoriously difficult to produce. Typical challenges associated with (18)F radiochemistry are the short half-life of (18)F (<2 h), the use of sub-stoichiometric amounts of (18)F, relative to the precursor and other reagents, as well as the limited availa...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
A broadly applicable [18F]trifluoromethylation of aryl and heteroaryl iodides for PET imaging.
If you are the owner of this record, you can report an update to it here: Report update to this record