Journal article icon

Journal article

Identification of an immunodominant region of the major house dust mite allergen Der p 2 presented by common human leucocyte antigen alleles.

Abstract:

BACKGROUND: Better understanding of the relevance of the immune response to common environmental allergens, such as the major house dust mite (HDM) allergen Der p 2, requires characterization of constituent T-cell epitopes. AIM: To identify CD4(+) T-cell epitopes within Der p 2 recognized by commonly expressed human leucocyte antigen (HLA) alleles. METHODS: HLA-blocking antibodies, peptide pools and truncations were used in ELISpot assays to establish restricted T-cell epitopes. RESULTS: Peop...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Journal:
Clinical and experimental dermatology
Volume:
37
Issue:
3
Pages:
266-276
Publication date:
2012-04-05
DOI:
EISSN:
1365-2230
ISSN:
0307-6938
URN:
uuid:4a810527-b676-4e58-ba8a-3762736e0e63
Source identifiers:
221316
Local pid:
pubs:221316

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP