- Abstract:
-
BACKGROUND: Better understanding of the relevance of the immune response to common environmental allergens, such as the major house dust mite (HDM) allergen Der p 2, requires characterization of constituent T-cell epitopes. AIM: To identify CD4(+) T-cell epitopes within Der p 2 recognized by commonly expressed human leucocyte antigen (HLA) alleles. METHODS: HLA-blocking antibodies, peptide pools and truncations were used in ELISpot assays to establish restricted T-cell epitopes. RESULTS: Peop...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1111/j.1365-2230.2011.04227.x
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- Journal:
- Clinical and experimental dermatology
- Volume:
- 37
- Issue:
- 3
- Pages:
- 266-276
- Publication date:
- 2012-04-05
- DOI:
- EISSN:
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1365-2230
- ISSN:
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0307-6938
- URN:
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uuid:4a810527-b676-4e58-ba8a-3762736e0e63
- Source identifiers:
-
221316
- Local pid:
- pubs:221316
- Copyright date:
- 2012
Journal article
Identification of an immunodominant region of the major house dust mite allergen Der p 2 presented by common human leucocyte antigen alleles.
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