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What is the evidence of a role for host genetics in susceptibility to influenza A/H5N1?

Abstract:

The apparent family clustering of avian influenza A/H5N1 has led several groups to postulate the existence of a host genetic influence on susceptibility to A/H5N1, yet the role of host factors on the risk of A/H5N1 disease has received remarkably little attention compared to the efforts focused on viral factors. We examined the epidemiological patterns of human A/H5N1 cases, their possible explanations, and the plausibility of a host genetic effect on susceptibility to A/H5N1 infection. The p...

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Publication status:
Published

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Publisher copy:
10.1017/s0950268810000518

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Journal:
Epidemiology and infection
Volume:
138
Issue:
11
Pages:
1550-1558
Publication date:
2010-11-05
DOI:
EISSN:
1469-4409
ISSN:
0950-2688
URN:
uuid:4a6c3fdb-474b-402b-bc20-f6187edaf583
Source identifiers:
51918
Local pid:
pubs:51918

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