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Drosophila Sal and Salr are transcriptional repressors.

Abstract:

The SALL (Spalt-like) family of zinc-finger transcription factors is conserved in metazoans. In Drosophila Sal (Spalt) and Salr (Spalt-related) control the expression of genes involved in wing and central nervous system development, including cell adhesion and cytoskeletal proteins. In humans, SALL mutations associate with congenital disorders such as the Townes-Brocks and Okihiro syndromes. Human and Drosophila SALL proteins are modified by SUMO (small ubiquitin-related modifier), which infl...

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Publication status:
Published

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Publisher copy:
10.1042/bj20110229

Authors


Sánchez, J More by this author
Talamillo, A More by this author
González, M More by this author
Sánchez-Pulido, L More by this author
Jiménez, S More by this author
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Journal:
The Biochemical journal
Volume:
438
Issue:
3
Pages:
437-445
Publication date:
2011-09-05
DOI:
EISSN:
1470-8728
ISSN:
0264-6021
URN:
uuid:4a5024e1-5bab-4d83-b637-4d0030894b9b
Source identifiers:
237335
Local pid:
pubs:237335

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