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Journal article

IgG and complement deposition and neuronal loss in cats and humans with epilepsy and voltage-gated potassium channel complex antibodies.

Abstract:

Voltage-gated potassium channel complex (VGKC-complex) antibody (Ab) encephalitis is a well-recognized form of limbic encephalitis in humans, usually occurring in the absence of an underlying tumor. The patients have a subacute onset of seizures, magnetic resonance imaging findings suggestive of hippocampal inflammation, and high serum titers of Abs against proteins of the VGKC-complex, particularly leucine-rich, glioma-inactivated 1 (LGI1). Most patients are diagnosed promptly and recover su...

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Publication status:
Published

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Authors


Schmidt, P More by this author
Kneissl, S More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neurosciences
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Journal:
Journal of neuropathology and experimental neurology
Volume:
73
Issue:
5
Pages:
403-413
Publication date:
2014-05-05
DOI:
EISSN:
1554-6578
ISSN:
0022-3069
URN:
uuid:4a4813ca-9537-4434-8e24-0ff469cef385
Source identifiers:
463073
Local pid:
pubs:463073

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