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Scanning the human genome for signals of selection.

Abstract:

The search for adaptive evolution in the human genome has reached a new era with the advent of genome-wide surveys of genetic variation. However, making sense, let alone use, of such experiments is far from straightforward. Key problems include the way in which the data have been collected, the need to control for factors such as population history and variable recombination rates, which influence the discovery rates for both true and false positives, and the inherent difficulty of falsificat...

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Publication status:
Published

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Publisher copy:
10.1016/j.gde.2006.09.004

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine
Role:
Author
Journal:
Current opinion in genetics and development
Volume:
16
Issue:
6
Pages:
624-629
Publication date:
2006-12-05
DOI:
EISSN:
1879-0380
ISSN:
0959-437X
URN:
uuid:49c315b7-26cc-400b-a67b-de3f314b33e8
Source identifiers:
103160
Local pid:
pubs:103160

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