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Cotranslational protein folding - fact or fiction?

Abstract:

Motivation: Experimentalists have amassed extensive evidence over the past four decades that proteins appear to fold during production by the ribosome. Protein structure prediction methods, however, do not incorporate this property of folding. A thorough study to find the fingerprint of such sequential folding is the first step towards using it in folding algorithms, so assisting structure prediction. Results: We explore computationally the existence of evidence for cotranslational folding, b...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/bioinformatics/btm175

Authors


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Institution:
University of Oxford
Research group:
Oxford Protein Informatics Group
Department:
Mathematical,Physical & Life Sciences Division - Statistics
Role:
Author
More by this author
Institution:
Macquarie University, NSW, Australia
Department:
Department of Statistics
Role:
Author
More by this author
Institution:
Macquarie University, NSW, Australia
Department:
Department of Statistics
Role:
Author
More by this author
Institution:
Macquarie University, NSW, Australia
Department:
Department of Statistics
Role:
Author
More by this author
Institution:
Macquarie University, NSW, Australia
Role:
Author
Publisher:
Oxford University Press Publisher's website
Journal:
Bioinformatics Journal website
Volume:
23
Issue:
13
Pages:
i142-i148
Publication date:
2007-07-05
DOI:
EISSN:
1460-2059
ISSN:
1367-4803
URN:
uuid:49b58ec2-57af-4147-a409-d3f4bf29a688
Local pid:
ora:1812

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