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The next 10 years for tuberculosis vaccines: do we have the right plans in place?

Abstract:

The control of TB is a global health priority. Over the last decade, considerable progress has been made in the field of TB vaccines with numerous vaccine candidates entering the clinic and two candidates now in Phase IIb efficacy trials. Nevertheless, the lack of predictive animal models and biomarkers of TB vaccine efficacy prevents rational vaccine down-selection and necessitates prolonged and expensive clinical efficacy trials in target populations. Advances in molecular technology and pr...

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Publication status:
Published

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Publisher copy:
10.1586/erv.13.19

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Journal:
Expert review of vaccines
Volume:
12
Issue:
4
Pages:
443-451
Publication date:
2013-04-05
DOI:
EISSN:
1744-8395
ISSN:
1476-0584
URN:
uuid:4996d1fb-7987-4610-949a-49e17dd82a26
Source identifiers:
394928
Local pid:
pubs:394928

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