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Three-dimensional electron ptychography of organic-inorganic hybrid nanostructures

Abstract:

Three dimensional scaffolded DNA origami with inorganic nanoparticles has been used to create tailored multidimensional nanostructures. However, the image contrast of DNA is poorer than those of the heavy nanoparticles in conventional transmission electron microscopy at high defocus so that the biological and non-biological components in 3D scaffolds cannot be simultaneously resolved using tomography of samples in a native state. We demonstrate the use of electron ptychography to recover high...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41467-022-32548-x

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Materials
Role:
Author
ORCID:
0000-0001-6827-425X
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Materials
Role:
Author
ORCID:
0000-0002-7864-8427
Publisher:
Springer
Journal:
Nature Communications More from this journal
Volume:
13
Issue:
1
Article number:
4787
Place of publication:
England
Publication date:
2022-08-15
Acceptance date:
2022-08-04
DOI:
ISSN:
2041-1723
Pmid:
35970924
Language:
English
Keywords:
Pubs id:
1274909
Local pid:
pubs:1274909
Deposit date:
2024-03-07

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