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Slow wave sleep and 5-HT2 receptor sensitivity in generalised anxiety disorder: a pilot study with ritanserin.

Abstract:

Eight patients with generalised anxiety disorder (GAD) and eight matched healthy controls had their polysomnogram measured on two occasions separated by 1 week. On one occasion they received the 5-HT2 receptor antagonist, ritanserin (5 mg orally) and on the other matching placebo. The increase in slow wave sleep produced by ritanserin was the same in GAD patients as in healthy controls. These findings do not support the hypothesis that GAD is associated with a generalised hypersensitivity of ...

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Publication status:
Published

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Publisher copy:
10.1007/bf02245128

Authors


da Roza Davis, JM More by this author
Sharpley, AL More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Journal:
Psychopharmacology
Volume:
108
Issue:
3
Pages:
387-389
Publication date:
1992-01-05
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
URN:
uuid:49825ab8-2d49-4d8e-87d6-b5181aa3d666
Source identifiers:
185801
Local pid:
pubs:185801

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