Journal article icon

Journal article

Long-term humoral and cellular immune responses elicited by a heterologous Plasmodium vivax apical membrane antigen 1 protein prime/adenovirus boost immunization protocol.

Abstract:

Apical membrane antigen 1 (AMA-1) is an invasion-related Plasmodium antigen that is expressed during both intracellular and extracellular asexual stages of the parasite's life cycle, making it an ideal target for induction of humoral and cellular immune responses that can protect against malaria. We show here that when it is administered as a recombinant protein (P) in Montanide ISA720 adjuvant, followed by a recombinant human type 5 adenovirus (Ad), intense and long-lasting Plasmodium vivax ...

Expand abstract

Actions


Access Document


Publisher copy:
10.1128/IAI.05048-11

Authors


Expand authors...
Journal:
Infect Immun
Volume:
79
Issue:
9
Pages:
3642-3652
Publication date:
2011-09-05
DOI:
EISSN:
1098-5522
ISSN:
0019-9567
URN:
uuid:4933138d-d24b-4139-8939-2e55f06d91e0
Source identifiers:
163987
Local pid:
pubs:163987

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP