Journal article icon

Journal article

Acetylcholine receptors loss and postsynaptic damage in MuSK antibody-positive myasthenia gravis.

Abstract:

Muscle-specific tyrosine kinase (MuSK) antibodies are found in some patients with "seronegative" myasthenia gravis (MG), but how they cause myasthenic symptoms is not clear. We visualized acetylcholine receptors (AChRs) and complement component 3 (C3) in muscle biopsies from 10 Japanese MG patients with MuSK antibodies, compared with 42 with AChR antibodies. The AChR density was not significantly decreased in MuSK antibody (Ab)-positive end-plates compared with AChR antibody-positive end-plat...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1002/ana.20341

Authors


Shiraishi, H More by this author
Motomura, M More by this author
Yoshimura, T More by this author
Fukudome, T More by this author
Expand authors...
Journal:
Annals of neurology
Volume:
57
Issue:
2
Pages:
289-293
Publication date:
2005-02-05
DOI:
EISSN:
1531-8249
ISSN:
0364-5134
URN:
uuid:4926bad5-9ccb-4493-8dc5-131845197ccb
Source identifiers:
242727
Local pid:
pubs:242727

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP