- Abstract:
-
In order to study the pharmacokinetic properties of amodiaquine and desethylamodiaquine during pregnancy, 24 pregnant women in the second and third trimesters of pregnancy and with Plasmodium vivax malaria were treated with amodiaquine (10 mg/kg of body weight/day) for 3 days. The same women were studied again at 3 months postpartum. Plasma was analyzed for amodiaquine and desethylamodiaquine by use of a liquid chromatography-tandem mass spectrometry method. Individual concentration-time data...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1128/aac.00154-11
-
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- Journal:
- Antimicrobial agents and chemotherapy
- Volume:
- 55
- Issue:
- 9
- Pages:
- 4338-4342
- Publication date:
- 2011-09-05
- DOI:
- EISSN:
-
1098-6596
- ISSN:
-
0066-4804
- URN:
-
uuid:49108f9c-6fcb-4f2e-a99e-9e5f2b230364
- Source identifiers:
-
163940
- Local pid:
- pubs:163940
- Language:
- English
- Keywords:
- Copyright date:
- 2011
Journal article
Pharmacokinetics of amodiaquine and desethylamodiaquine in pregnant and postpartum women with Plasmodium vivax malaria.
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