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Cdc14-dependent dephosphorylation of a kinetochore protein prior to anaphase in Saccharomyces cerevisiae.

Abstract:
The budding yeast Cdc14 phosphatase reverses Cdk1 phosphorylation to promote mitotic exit. Although Cdc14 activity is thought to be restricted to anaphase, we found that dephosphorylation of the Dsn1 kinetochore protein in metaphase requires Cdc14. These data suggest that there is a nonnucleolar pool of active Cdc14 prior to anaphase.

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Publisher copy:
10.1534/genetics.110.123653

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Biggins, S More by this author
Journal:
Genetics
Volume:
186
Issue:
4
Pages:
1487-1491
Publication date:
2010-12-05
DOI:
EISSN:
1943-2631
ISSN:
0016-6731
URN:
uuid:48f9bc95-3796-4048-b128-8749603b0772
Source identifiers:
228690
Local pid:
pubs:228690

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