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Journal article

The association of HLA DR beta alleles with self-limiting and persistent forms of early symmetrical polyarthritis.

Abstract:

RA is associated with a group of class II DR beta alleles, which share a conserved sequence in the third allelic hypervariable region (3AHVR). These include the DR4 subtypes Dw4, Dw14 and Dw15, and also DR1. In contrast Dw10 and Dw13 which are also DR4 subtypes show no association with RA and have a quite distinct 3AHVR. We have assessed the frequency of these alleles in 55 patients who initially presented with symmetrical peripheral polyarthritis suggestive of RA. After 4 years 27 had progre...

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Publication status:
Published

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Journal:
British journal of rheumatology
Volume:
32
Issue:
7
Pages:
628-630
Publication date:
1993-07-05
ISSN:
0263-7103
URN:
uuid:48d861f6-3d1a-4522-a5bb-4c3747233452
Source identifiers:
108825
Local pid:
pubs:108825

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