- Abstract:
-
UNLABELLED: Bisphosphonates can increase bone mineral density (BMD) in children with osteogenesis imperfecta (OI). In this study of adults with OI type I, risedronate increased BMD at lumbar spine (but not total hip) and decreased bone turnover. However, the fracture rate in these patients remained high. INTRODUCTION: Intravenous bisphosphonates given to children with OI can increase BMD and reduce fracture incidence. Oral and/or intravenous bisphosphonates may have similar effects in adults...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1007/s00198-011-1658-2
-
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- Journal:
- Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
- Volume:
- 23
- Issue:
- 1
- Pages:
- 285-294
- Publication date:
- 2012-01-05
- DOI:
- EISSN:
-
1433-2965
- ISSN:
-
0937-941X
- URN:
-
uuid:48c9dd9c-ab17-4e8e-b091-06dfda3d3883
- Source identifiers:
-
246069
- Local pid:
- pubs:246069
- Copyright date:
- 2012
Journal article
Risedronate in adults with osteogenesis imperfecta type I: increased bone mineral density and decreased bone turnover, but high fracture rate persists.
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