- Abstract:
-
Excessive synchronisation of basal ganglia activity at frequencies < 30 Hz is a hallmark of the parkinsonian state, and may contribute to bradykinesia. Accordingly, we electrically stimulated chronically implanted subthalamic macroelectrodes in 10 Parkinson's disease patients, after overnight withdrawal of anti-parkinsonian medication. We compared the effects of stimulation at 0, 5, 10, 15, 20, 25, 30, and ca. 130 Hz by measuring kinesia time (KT) in a tapping task. Although the effects of...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.neulet.2005.02.050
-
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- Journal:
- Neuroscience letters
- Volume:
- 382
- Issue:
- 1-2
- Pages:
- 5-9
- Publication date:
- 2005-01-01
- DOI:
- EISSN:
-
1872-7972
- ISSN:
-
0304-3940
- URN:
-
uuid:48c54b71-0c92-47c3-a177-fbf177223f06
- Source identifiers:
-
122448
- Local pid:
- pubs:122448
- Copyright date:
- 2005
Journal article
Frequency dependent effects of subthalamic nucleus stimulation in Parkinson's disease.
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