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Anti-streptokinase antibody inhibition of streptokinase induced fibrinolysis following intra-pleural streptokinase

Abstract:

Background. Anti-streptokinase immunoglobulin (IgG) induced by intravenous (IV) streptokinase (SK) can reduce the effectiveness of repeated SK use, or lead to an increased incidence of immune mediated adverse reactions. It is therefore advised that IV SK exposed patients receive an alternative fibrinolytic for later exposures. It is not known whether intra-pleural streptokinase (IPSK) induces a similar response. Methods. We studied 18 patients (age 35-81) receiving IPSK for drainage of multil...

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
Journal:
Thorax
Volume:
53
Issue:
SUPPL. 4
Publication date:
1998-12-05
ISSN:
0040-6376
URN:
uuid:489cf8f5-e847-4ad6-8ca2-ebd0e56fcb9e
Source identifiers:
80085
Local pid:
pubs:80085
Language:
English

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