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Journal article

Evaluation of a standardised Vi poly-l-lysine ELISA for serology of Vi capsular polysaccharide antibodies

Abstract:

Typhoid vaccines based on protein-conjugated capsular Vi polysaccharide (TCVs) prevent typhoid in infants and young children. Analysis of the serum anti-Vi IgG response following immunisation against typhoid confirms the immunogenicity of TCVs and forms an important part of the pathway to licensing. Comparative studies could expedite the licencing process, and the availability of a standardised ELISA method alongside the 1st International Standard (IS) 16/138 for anti-typhoid capsular Vi poly...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


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Bill & Melinda Gates Foundation More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Biologicals Journal website
Publication date:
2020-06-20
Acceptance date:
2020-05-15
DOI:
EISSN:
1095-8320
ISSN:
1045-1056
Pmid:
32571662
Pubs id:
1114868
Local pid:
pubs:1114868
Language:
English
Keywords:
Format:
Print-Electronic

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