Typhoid vaccines based on protein-conjugated capsular Vi polysaccharide (TCVs) prevent typhoid in infants and young children. Analysis of the serum anti-Vi IgG response following immunisation against typhoid confirms the immunogenicity of TCVs and forms an important part of the pathway to licensing. Comparative studies could expedite the licencing process, and the availability of a standardised ELISA method alongside the 1st International Standard (IS) 16/138 for anti-typhoid capsular Vi poly...Expand abstract
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- Peer review status:
- Peer reviewed
- Copyright holder:
- Peter Rigsby et al.
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- © 2020 The Author(s). Published by Elsevier Ltd on behalf of International Alliance for Biological Standardization. This is an open access article under the CC BY license (http://creativecommons.org/licenses/BY/4.0/).
- CC Attribution (CC BY)
Evaluation of a standardised Vi poly-l-lysine ELISA for serology of Vi capsular polysaccharide antibodies
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