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Journal article

Multiple sclerosis and lung cancer: an unexpected inverse association.

Abstract:
Multiple sclerosis is associated with a decreased risk of cancer. Smoking is a risk factor both for multiple sclerosis and lung cancer. We performed a meta-analysis on studies of cancer frequency in multiple sclerosis. Surprisingly, we found that the risk of lung cancer is reduced in multiple sclerosis [odds ratio 0.67 (95% confidence interval 0.59-0.76) P < 0.00001]. Since this does not appear to be secondary to altered smoking behaviour, we hypothesise that this may be secondary to altered immune surveillance.
Publication status:
Published

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Publisher copy:
10.1093/qjmed/hcq071

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Journal:
QJM : monthly journal of the Association of Physicians
Volume:
103
Issue:
8
Pages:
625-626
Publication date:
2010-08-05
DOI:
EISSN:
1460-2393
ISSN:
1460-2725
URN:
uuid:489201fc-30e3-406d-8ef6-a7771655638b
Source identifiers:
300018
Local pid:
pubs:300018

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