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The evolution of antibiotic resistance: insight into the roles of molecular mechanisms of resistance and treatment context.

Abstract:

The widespread use of antibiotics has markedly improved public health over the last 60 years. However, the efficacy of antibiotic treatment is rapidly decreasing as a result of the continual spread of antibiotic resistance in pathogen populations. The evolution of antibiotic resistance is an amazingly simple example of adaptation by natural selection, and there is growing interest among evolutionary biologists in using evolutionary principles to help understand and combat the spread of resist...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Perron, GG More by this author
Buckling, A More by this author
Journal:
Discovery medicine
Volume:
10
Issue:
51
Pages:
112-118
Publication date:
2010-08-05
EISSN:
1944-7930
ISSN:
1539-6509
URN:
uuid:4891d398-6c6f-4066-bae4-b7dea0764570
Source identifiers:
209828
Local pid:
pubs:209828

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