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Pathophysiology and immunology of the Jarisch-Herxheimer-like reaction in louse-borne relapsing fever: comparison of tetracycline and slow-release penicillin.

Abstract:

Twelve men with louse-borne relapsing fever were treated with single doses of procaine penicillin plus aluminum monostearate (PAM) intramuscularly or of tetracycline intravenously. All patients experienced a definite Jarisch-Herxheimer-like reaction. Fever and spirochetemia were significantly prolonged and peak temperature was lower and occurred later in the PAM-treated group. Peak pulmonary ventilation, metabolic rate, and arterial PO2 were significantly higher in the tetracycline-treated gr...

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Publication status:
Published

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Publisher copy:
10.1093/infdis/147.5.898

Authors


Journal:
Journal of infectious diseases
Volume:
147
Issue:
5
Pages:
898-909
Publication date:
1983-05-01
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
Source identifiers:
61142
Language:
English
Keywords:
Pubs id:
pubs:61142
UUID:
uuid:48880046-75be-4bf2-b0fc-198aede689c3
Local pid:
pubs:61142
Deposit date:
2012-12-19

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