Journal article icon

Journal article

Multivalent recombinant proteins for probing functions of leucocyte surface proteins such as the CD200 receptor

Abstract:

CD200 (OX2) is a membrane glycoprotein that interacts with a structurally related receptor (CD200R) involved in the regulation of macrophage function. The interaction is of low affinity (K D ∼ 1 μm) but can be detected using CD200 displayed in a multivalent form on beads or with dimeric fusion proteins consisting of the extracellular region of CD200 and immunoglobulin Fc regions. We prepared putative pentamers and trimers of mouse CD200 with sequences from cartilage ol...

Expand abstract

Actions


Access Document


Authors


Voulgaraki, D More by this author
Mitnacht-Kraus, R More by this author
Letarte, M More by this author
Foster-Cuevas, M More by this author
Expand authors...
Journal:
Immunology
Volume:
115
Issue:
3
Pages:
337-346
Publication date:
2005-07-05
DOI:
ISSN:
0019-2805
URN:
uuid:487ce1d7-469a-4a92-b1d6-e7a17a823062
Source identifiers:
171851
Local pid:
pubs:171851
Language:
English
Keywords:

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP