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Journal article

The dementia-associated APOE ε4 allele is not associated with rapid eye movement sleep behavior disorder

Abstract:

The present study aimed to examine whether the APOE ε4 allele, associated with dementia with Lewy bodies (DLB), and possibly with dementia in Parkinson's disease (PD), is also associated with idiopathic rapid eye movement sleep behavior disorder (RBD). Two single nucleotide polymorphisms, rs429358 and rs7412, were genotyped in RBD patients (n = 480) and in controls (n = 823). APOE ε4 allele frequency was 0.14 among RBD patients and 0.13 among controls (OR = 1.11, 95% CI: 0.88-1.40, p = 0.41)....

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Authors


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Michael J. Fox Foundation for Parkinson's Research More from this funder
Weston Brain Institute More from this funder
J.L. Levesque Foundation More from this funder
Lowensteinstiftung More from this funder
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Publisher:
Elsevier Publisher's website
Journal:
Neurobiology of Aging Journal website
Volume:
49
Pages:
218.e13–218.e15
Publication date:
2016-10-13
DOI:
EISSN:
1558-1497
ISSN:
0197-4580
Pubs id:
pubs:660166
URN:
uri:48705a5c-2b15-4677-90ec-5163bf670332
UUID:
uuid:48705a5c-2b15-4677-90ec-5163bf670332
Local pid:
pubs:660166

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