- Abstract:
-
The dorsal and median raphe nuclei were examined with immunocytochemistry to display the 5-HT neurones in 16 cases of post-mortem-proven Alzheimer's disease (AD) and 12 age and sex-matched controls. The AD cases had been prospectively assessed during life for expression of behavioural changes as well as for cognitive decline. A significant (P < 0.001) 41% reduction in density of dorsal raphe neurones was found along with a significant (P < 0.02) 29% reduction in density of median raphe ...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1046/j.1365-2990.2000.00254.x
-
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- Journal:
- Neuropathology and applied neurobiology
- Volume:
- 26
- Issue:
- 4
- Pages:
- 347-355
- Publication date:
- 2000-08-05
- DOI:
- EISSN:
-
1365-2990
- ISSN:
-
0305-1846
- URN:
-
uuid:48459373-a857-4589-ab09-8371f906ce65
- Source identifiers:
-
242254
- Local pid:
- pubs:242254
- Copyright date:
- 2000
Journal article
Immunocytochemical study of the dorsal and median raphe nuclei in patients with Alzheimer's disease prospectively assessed for behavioural changes.
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