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Journal article

Tumour-infiltrating lymphocytes predict response to definitive chemoradiotherapy in head and neck cancer

Abstract:

Background:We aimed to investigate the prognostic value of tumour-infiltrating lymphocytes' (TILs) expression in pretreatment specimens from patients with head and neck squamous cell carcinoma (HNSCC) treated with definitive chemoradiotherapy (CRT).Methods:The prevalence of CD3+, CD8+, CD4+ and FOXP3+ TILs was assessed using immunohistochemistry in tumour tissue obtained from 101 patients before CRT and was correlated with clinicopathological characteristics as well as local failure-free-(LFF...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/bjc.2013.640

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Publisher:
Cancer Research UK Publisher's website
Journal:
British Journal of Cancer Journal website
Volume:
110
Issue:
2
Pages:
501-509
Publication date:
2014-01-01
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
URN:
uuid:48455596-b02f-41ae-af22-4d029777b121
Source identifiers:
448260
Local pid:
pubs:448260

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