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Direct membrane binding by bacterial actin MreB.

Abstract:

Bacterial actin MreB is one of the key components of the bacterial cytoskeleton. It assembles into short filaments that lie just underneath the membrane and organize the cell wall synthesis machinery. Here we show that MreB from both T. maritima and E. coli binds directly to cell membranes. This function is essential for cell shape determination in E. coli and is proposed to be a general property of many, if not all, MreBs. We demonstrate that membrane binding is mediated by a membrane insert...

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Role:
Author
Journal:
Molecular cell
Volume:
43
Issue:
3
Pages:
478-487
Publication date:
2011-08-05
DOI:
EISSN:
1097-4164
ISSN:
1097-2765
URN:
uuid:47deb4dc-b36f-491c-850b-7000bebf6b34
Source identifiers:
432088
Local pid:
pubs:432088

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