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Journal article

The dynamics of the cellular immune response to HIV infection: implications for vaccination.

Abstract:

Recent advances in measuring T-cell responses to viruses have led to new insights into how these T cells respond. In the acute infection there are massive CD8+ T-cell responses to both Epstein-Barr virus (EBV) and to human immunodeficiency virus (HIV). Many of these T cells are effector cells and only a minority appear to be capable of maintaining immunological memory. In persistent virus infections, high levels of antigen-specific effector cells persist. If virus does not persist, the effect...

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Publication status:
Published

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Publisher copy:
10.1098/rstb.2000.0637

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
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Journal:
Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Volume:
355
Issue:
1400
Pages:
1007-1011
Publication date:
2000-08-05
DOI:
EISSN:
1471-2970
ISSN:
0962-8436
URN:
uuid:478a79de-8e7f-42d9-9c62-ecdc535e9724
Source identifiers:
31816
Local pid:
pubs:31816

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