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Adipokines, adiposity, and bone marrow adipocytes: Dangerous accomplices in multiple myeloma

Abstract:

Obesity has become a global epidemic influencing the establishment and progression of a wide range of diseases, such as diabetes, cardiovascular disease, and cancer. In 2016, International Agency for Research on Cancer reported that obesity is now associated with 13 different cancers, one of which is multiple myeloma (MM), a destructive cancer of plasma cells that predominantly reside in the bone marrow. Obesity is the accumulation of excess body fat, which causes metabolic, endocrine, immuno...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1002/jcp.26884

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Oxford college:
St Edmund Hall
ORCID:
0000-0002-1257-5659
National Institute for Health Research More from this funder
Publisher:
Wiley Publisher's website
Journal:
Journal of Cellular Physiology Journal website
Volume:
233
Issue:
12
Pages:
9159-9166
Publication date:
2018-06-26
Acceptance date:
2018-05-23
DOI:
EISSN:
1097-4652
ISSN:
0021-9541
Pubs id:
pubs:859577
URN:
uri:477cef78-dbed-4b2a-826f-1750453089fb
UUID:
uuid:477cef78-dbed-4b2a-826f-1750453089fb
Local pid:
pubs:859577

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