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A study of CSF idiotypes in multiple sclerosis.

Abstract:

Six anti-idiotypic antisera have been raised against isolated cerebrospinal fluid (CSF) bands from five patients with multiple sclerosis and against a serum band from an additional patient. Preparative isoelectric focusing in agarose was useful for isolating highly purified bands. Individual antigenic specificities defined by these antisera were not detected on other bands from the same patients or in IgG isolated from the CSF of other patients. The CSF to serum ratios of the idiotypic determ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, WTC Human Genetics
Journal:
Scandinavian journal of immunology
Volume:
16
Issue:
2
Pages:
151-161
Publication date:
1982-08-05
DOI:
EISSN:
1365-3083
ISSN:
0300-9475
URN:
uuid:477b6976-b52c-4840-a820-30bc60f639c7
Source identifiers:
35444
Local pid:
pubs:35444

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