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Journal article

Migratory sub-populations of afferent lymphatic dendritic cells differ in their interactions with Mycobacterium bovis Bacille Calmette Guerin.

Abstract:

Understanding how pathogens or vaccine antigens are targeted to dendritic cell (DC) subsets is important for disease pathogenesis studies and vaccine design. We characterised the sub-populations of migrating bovine DC with functional and phenotypic diversity present in pseudoafferent lymph draining the skin. These skin draining DC exist as a series of maturation dependent subsets with differential capacities for antigen uptake and cytokine expression, and include both Langerhans' cells (LC) a...

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Publication status:
Published

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Authors


Cubillos-Zapata, C More by this author
Stephens, SA More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
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Journal:
Vaccine
Volume:
30
Issue:
13
Pages:
2357-2367
Publication date:
2012-03-05
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
URN:
uuid:47665196-9b9a-48f3-8b68-5a55ad4ce2cf
Source identifiers:
314049
Local pid:
pubs:314049

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