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MR spectroscopy in heart failure--clinical and experimental findings.

Abstract:

Magnetic resonance spectroscopy (MRS) allows for the non-invasive detection of a wide variety of metabolites in the heart. To study the metabolic changes that occur in heart failure, (31)P- and (1)H-MRS have been applied in both patients and experimental animal studies. (31)P-MRS allows for the detection of phosphocreatine (PCr), ATP, inorganic phosphate (Pi) and intracellular pH, while (1)H-MRS allows for the detection of total creatine. All these compounds are involved in the regulation of ...

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Publication status:
Published

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Publisher copy:
10.1007/s10741-007-9003-8

Authors


Ten Hove, M More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine, BHF Centre of Research Excellence
Journal:
Heart failure reviews
Volume:
12
Issue:
1
Pages:
48-57
Publication date:
2007-03-05
DOI:
EISSN:
1573-7322
ISSN:
1382-4147
URN:
uuid:475bb233-a7b1-4147-ac6d-c552a8baa900
Source identifiers:
124779
Local pid:
pubs:124779

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