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Journal article

Affinity and kinetic analysis of the interaction of the cell adhesion molecules rat CD2 and CD48.

Abstract:

CD2 is a plasma membrane glycoprotein present on T lymphocytes that functions as a cell adhesion molecule (CAM). The CD2 counter-receptor in rodents is the structurally-related CAM CD48. Intercellular adhesion involves the formation of multiple CAM complexes between adhering cells and de-adhesion requires disruption of these complexes. To gain an insight into the initiation and termination of intercellular adhesion, the kinetics and affinity of the rat CD2-CD48 interaction was analysed using ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
Barclay, AN More by this author
Journal:
The EMBO journal
Volume:
12
Issue:
13
Pages:
4945-4954
Publication date:
1993-12-05
EISSN:
1460-2075
ISSN:
0261-4189
URN:
uuid:4738dee0-4b4f-4425-828b-fe3b1020cf89
Source identifiers:
27878
Local pid:
pubs:27878

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