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Journal article

Equilibration in bicyclic pyroglutamates by ring opening-reclosure

Abstract:
Enantiopure bicyclic tetramates, readily obtained by Dieckmann ring closure on oxazolidine-derived templates, can be further converted to hydroxypyroglutamates by kinetically controlled nucleophilic additions, and some of these products are capable of equilibration via a facile retro-aldol/aldol reclosure. © 2008 Elsevier Ltd. All rights reserved.
Publication status:
Published

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Publisher copy:
10.1016/j.tetlet.2008.08.021

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
TETRAHEDRON LETTERS More from this journal
Volume:
49
Issue:
43
Pages:
6202-6204
Publication date:
2008-10-20
DOI:
ISSN:
0040-4039


Language:
English
Pubs id:
pubs:40914
UUID:
uuid:4723f32e-14b1-4269-b893-ab69a2bf18ee
Local pid:
pubs:40914
Source identifiers:
40914
Deposit date:
2012-12-19

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