Journal article
Application of stochastic phenomenological modelling to cell-to-cell and beat-to-beat electrophysiological variability in cardiac tissue
- Abstract:
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Variability in the action potential of isolated myocytes and tissue samples is observed in experimental studies. Variability is manifested as both differences in the action potential (AP) morphology between cells (extrinsic variability), and also ‘intrinsic’ or beat-to-beat variability of repolarization (BVR) in the AP duration of each cell. We studied the relative contributions of experimentally recorded intrinsic and extrinsic variability to dispersion of repolarization in tissue. We develo...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.4MB)
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- Publisher copy:
- 10.1016/j.jtbi.2014.10.029
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Authors
Funding
+ Engineering and Physical Sciences Research Council
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Funding agency for:
Walmsley, J
+ Engineering and Physical Sciences Research Council
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Funding agency for:
Mirams, GR
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Journal of Theoretical Biology Journal website
- Volume:
- 365
- Pages:
- 325-336
- Publication date:
- 2014-11-04
- Acceptance date:
- 2014-10-23
- DOI:
- EISSN:
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1095-8541
- ISSN:
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0022-5193
- Source identifiers:
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492810
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:492810
- UUID:
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uuid:47180f35-ef32-4378-a915-28e3c2e378af
- Local pid:
- pubs:492810
- Deposit date:
- 2015-11-12
Terms of use
- Copyright holder:
- Walmsley et al
- Copyright date:
- 2014
- Rights statement:
- Copyright © 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).
- Licence:
- CC Attribution (CC BY)
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