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Journal article

Guidelines for the measurement of BCR-ABL1 transcripts in chronic myeloid leukaemia.

Abstract:

Molecular testing for the BCR-ABL1 fusion gene by real time quantitative polymerase chain reaction (RT-qPCR) is the most sensitive routine approach for monitoring the response to therapy of patients with chronic myeloid leukaemia. In the context of tyrosine kinase inhibitor (TKI) therapy, the technique is most appropriate for patients who have achieved complete cytogenetic remission and can be used to define specific therapeutic milestones. To achieve this effectively, standardization of the ...

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Publication status:
Published

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Journal:
British journal of haematology
Volume:
153
Issue:
2
Pages:
179-190
Publication date:
2011-04-01
DOI:
EISSN:
1365-2141
ISSN:
0007-1048
Source identifiers:
124330

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