- Abstract:
- We have identified an HLA-A2-restricted CD8(+) T-cell epitope, FLYALALLL, in the Epstein-Barr virus (EBV) latent membrane protein 2 (LMP2), an important target antigen in the context of EBV-associated malignancies. This epitope is TAP independent, like other hydrophobic LMP2-derived epitopes, but uniquely is dependent upon the immunoproteasome for its generation.
- Publication status:
- Published
- Publisher copy:
- 10.1128/jvi.77.4.2757-2761.2003
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- Journal:
- Journal of virology
- Volume:
- 77
- Issue:
- 4
- Pages:
- 2757-2761
- Publication date:
- 2003-02-05
- DOI:
- EISSN:
-
1098-5514
- ISSN:
-
0022-538X
- URN:
-
uuid:46f1bbfd-c5b3-4df6-9e62-94ea5e2d160d
- Source identifiers:
-
32301
- Local pid:
- pubs:32301
- Copyright date:
- 2003
Journal article
Identification of a TAP-independent, immunoproteasome-dependent CD8+ T-cell epitope in Epstein-Barr virus latent membrane protein 2.
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