Journal article icon

Journal article

Identification of a TAP-independent, immunoproteasome-dependent CD8+ T-cell epitope in Epstein-Barr virus latent membrane protein 2.

Abstract:
We have identified an HLA-A2-restricted CD8(+) T-cell epitope, FLYALALLL, in the Epstein-Barr virus (EBV) latent membrane protein 2 (LMP2), an important target antigen in the context of EBV-associated malignancies. This epitope is TAP independent, like other hydrophobic LMP2-derived epitopes, but uniquely is dependent upon the immunoproteasome for its generation.
Publication status:
Published

Actions


Access Document


Authors


Expand authors...
Journal:
Journal of virology
Volume:
77
Issue:
4
Pages:
2757-2761
Publication date:
2003-02-05
DOI:
EISSN:
1098-5514
ISSN:
0022-538X
URN:
uuid:46f1bbfd-c5b3-4df6-9e62-94ea5e2d160d
Source identifiers:
32301
Local pid:
pubs:32301

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP