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Cerebral subcortical small vessel disease in subjects with pathologically confirmed alzheimer disease: A clinicopathologic study in the oxford project to investigate memory and ageing (OPTIMA)

Abstract:

The understanding of how cerebrovascular disease (CVD) contributes to dementia is hampered by a lack of agreed and validated pathologic methods to accord weight to the contribution of different aspects of CVD to dementia. A previous study from the Oxford Project to Investigate Memory and Ageing (OPTIMA) validated a scheme for assessing the contribution of subcortical small vessel disease (SVD) toward dementia in the elderly by showing a significant inverse relationship between the severity of...

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Authors


Joachim, C More by this author
Christie, S More by this author
Agacinski, G More by this author
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Journal:
Alzheimer Disease and Associated Disorders
Volume:
28
Issue:
1
Pages:
30-35
Publication date:
2014-01-05
DOI:
ISSN:
0893-0341
URN:
uuid:46eb6045-b54b-4575-8b3d-e03226561c41
Source identifiers:
452078
Local pid:
pubs:452078

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