Journal article
Proteo-metabolomics reveals compensation between ischemic and non-injured contralateral kidneys after reperfusion
- Abstract:
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Ischaemia and reperfusion injury (IRI) is the leading cause of acute kidney injury (AKI), which contributes to high morbidity and mortality rates in a wide range of injuries as well as the development of chronic kidney disease. The cellular and molecular responses of the kidney to IRI are complex and not fully understood. Here, we used an integrated proteomic and metabolomic approach to investigate the effects of IRI on protein abundance and metabolite levels. Rat kidneys were subjected to 45...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 4.5MB)
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- Publisher copy:
- 10.1038/s41598-018-26804-8
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Authors
Funding
+ NHS Blood and Transplant Trust Fund
More from this funder
Funding agency for:
Kaisar, M
Grant:
TF031
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Bibliographic Details
- Publisher:
- Nature Publishing Group: Publisher's website
- Journal:
- Scientific Reports Journal website
- Volume:
- 8
- Article number:
- 8539
- Publication date:
- 2018-06-04
- Acceptance date:
- 2018-05-18
- DOI:
- ISSN:
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2045-2322
- Source identifiers:
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855750
Item Description
- Pubs id:
-
pubs:855750
- UUID:
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uuid:46bf3314-e2a1-4481-a2fb-cb7620e766f8
- Local pid:
- pubs:855750
- Deposit date:
- 2018-06-05
Terms of use
- Copyright holder:
- © Huang, et al
- Copyright date:
- 2018
- Notes:
- This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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