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Intravenous iron supplementation may protect against acute mountain sickness: a randomized, double-blinded, placebo-controlled trial.

Abstract:

Acute mountain sickness (AMS) is a common and disabling condition that occurs in healthy individuals ascending to high altitude. Based on the ability of iron to influence cellular oxygen sensing pathways, we hypothesized that iron supplementation would protect against AMS. To examine this hypothesis, 24 healthy sea-level residents were randomized to receive either intravenous iron(III)-hydroxide sucrose (200 mg) or saline placebo, before ascending rapidly to Cerro de Pasco, Peru (4340 m). The...

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Publication status:
Published

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Publisher copy:
10.1089/ham.2011.1005

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
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Journal:
High altitude medicine and biology
Volume:
12
Issue:
3
Pages:
265-269
Publication date:
2011-01-01
DOI:
EISSN:
1557-8682
ISSN:
1527-0297
URN:
uuid:469d0b36-9441-4925-9d5d-9eca7dd04281
Source identifiers:
186548
Local pid:
pubs:186548

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