Evaluation of sodium T1 relaxation times in human heart.

Journal article

PURPOSE: To evaluate the sodium longitudinal relaxation (T(1)) characteristics for myocardium and blood in humans. MATERIALS AND METHODS: Eleven healthy volunteers were examined by using a (23)Na heart surface coil at a 1.5 T clinical scanner equipped with a broadband spectroscopy option. (23)Na MR measurements were performed by using a three-dimensional spoiled gradient echo sequence (in-plane resolution, 3.5 mm x 7 mm; slice thickness, 24 mm; TE, 3.1 msec; bandwidth, 65 Hz/pixel; TR, 21 to 150 msec). RESULTS: Longitudinal T(1) relaxation time components were 31.6+/-7.0 msec and 31.1+/-7.5 msec for myocardium and blood, respectively. CONCLUSION: (23)Na T(1) relaxation times of myocardium and blood can be determined in humans. The results are in agreement with values obtained from animal studies.

Authors: Pabst, T; Sandstede, J; Beer, M; Kenn, W; Neubauer, S

• Publication status: Published
• Journal: Journal of magnetic resonance imaging : JMRI
• Volume: 17
• Issue: 6
• Pages: 726-729
• Publication date: 2003-06-01
• DOI: 10.1002/jmri.10310
• EISSN: 1522-2586
• ISSN: 1053-1807
• Language: English
• Keywords: Adult; Myocardium; Blood; Sodium Isotopes; Time Factors; Reference Values; Female; Sodium; Heart; Humans; Echocardiography, Three-Dimensional; Magnetic Resonance Imaging; Male