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Journal article

Comparing the role of the anterior cingulate cortex and 6-hydroxydopamine nucleus accumbens lesions on operant effort-based decision making.

Abstract:

Both the anterior cingulate cortex (ACC) and mesolimbic dopamine, particularly in the nucleus accumbens (NAc), have been implicated in allowing an animal to overcome effort constraints to obtain greater benefits. However, their exact contribution to such decisions has, to date, never been directly compared. To investigate this issue we tested rats on an operant effort-related cost-benefit decision-making task where animals selected between two response alternatives, one of which involved inve...

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Publication status:
Published

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Authors


Walton, ME More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Croxson, PL More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pharmacology
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Journal:
The European journal of neuroscience
Volume:
29
Issue:
8
Pages:
1678-1691
Publication date:
2009-04-05
DOI:
EISSN:
1460-9568
ISSN:
0953-816X
URN:
uuid:4681cacd-ba4e-4cf9-9cdc-0fbaea2c97d5
Source identifiers:
30352
Local pid:
pubs:30352

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