Journal article
Characteristics of the early immune response following transplantation of mouse ES cell derived insulin-producing cell clusters.
- Abstract:
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BACKGROUND: The fully differentiated progeny of ES cells (ESC) may eventually be used for cell replacement therapy (CRT). However, elements of the innate immune system may contribute to damage or destruction of these tissues when transplanted. METHODOLOGY/PRINCIPAL FINDINGS: Herein, we assessed the hitherto ill-defined contribution of the early innate immune response in CRT after transplantation of either ESC derived insulin producing cell clusters (IPCCs) or adult pancreatic islets. Ingress...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 2.1MB, Terms of use)
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- Publisher copy:
- 10.1371/journal.pone.0010965
Authors
Funding
+ Medical Research Council
More from this funder
Funding agency for:
Boyd, A
Grant:
grant P20RR018757
+ BD Preanalytical Systems Europe
More from this funder
Funding agency for:
Boyd, A
Grant:
grant P20RR018757
Bibliographic Details
- Publisher:
- Public Library of Science
- Journal:
- PloS one More from this journal
- Volume:
- 5
- Issue:
- 6
- Article number:
- e10965
- Publication date:
- 2010-06-04
- Acceptance date:
- 2010-02-22
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
Item Description
- Language:
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English
- Keywords:
- UUID:
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uuid:466d1302-9982-4597-93c4-8759d74ebd00
- Local pid:
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pubs:135994
- Source identifiers:
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135994
- Deposit date:
-
2012-12-19
Terms of use
- Copyright holder:
- Boyd, Wood
- Copyright date:
- 2010
- Notes:
- Copyright 2010 Boyd, Wood. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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