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Journal article

Characterization of blood dendritic and regulatory T cells in asymptomatic adults with sub-microscopic Plasmodium falciparum or Plasmodium vivax infection.

Abstract:

Background

Plasmodium falciparum and Plasmodium vivax infections compromise dendritic cell (DC) function and expand regulatory T (Treg) cells in both clinical disease (malaria) and experimental human sub-microscopic infection. Conversely, in asymptomatic microscopy-positive (patent) P. falciparum or P. vivax infection in endemic areas, blood DC increase or retain HLA-DR expression and Treg cells exhibit reduced activation, suggesting that DC and Treg cells contribute to the contro...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s12936-016-1382-7

Authors


Marfurt, J More by this author
Handayuni, I More by this author
Noviyanti, R More by this author
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Funding agency for:
Price, RN
Publisher:
BioMed Central Publisher's website
Journal:
Malaria journal Journal website
Volume:
15
Pages:
328
Publication date:
2016-06-05
DOI:
EISSN:
1475-2875
URN:
uuid:4660a51d-da69-4a79-9579-efa6a1ad1588
Source identifiers:
631397
Local pid:
pubs:631397

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