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Non-invasive preimplantation genetic testing (niPGT): the next revolution in reproductive genetics?

Abstract:

BACKGROUND: Preimplantation genetic testing (PGT) encompasses methods that allow embryos to be tested for severe inherited conditions or for chromosome abnormalities, relevant to embryo health and viability. In order to obtain embryonic genetic material for analysis, a biopsy is required, involving the removal of one or more cells. This invasive procedure greatly increases the costs of PGT and there have been concerns that embryo viability could be compromised in some cas... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/humupd/dmz033

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
Role:
Author
ORCID:
0000-0003-2633-9099


Publisher:
Oxford University Press
Journal:
Human Reproduction Update More from this journal
Volume:
26
Issue:
1
Pages:
16-42
Place of publication:
England
Publication date:
2019-11-27
DOI:
EISSN:
1460-2369
ISSN:
1355-4786
Pmid:
31774124

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