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RNA protects a nucleoprotein complex against radiation damage

Abstract:

Radiation damage during macromolecular X-ray crystallographic data collection is still the main impediment for many macromolecular structure determinations. Even when an eventual model results from the crystallographic pipeline, the manifestations of radiation-induced structural and conformation changes, so-called specific damage, within crystalline macromolecules can lead to false interpretations of biological mechanisms. Although this has been well characterised within protein crystals, far...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1107/S2059798316003351

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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
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Publisher:
International Union of Crystallography Publisher's website
Journal:
Acta Crystallographica Section D: Biological Crystallography Journal website
Publication date:
2016-05-01
DOI:
EISSN:
1399-0047
ISSN:
0907-4449
URN:
uuid:46111a6f-8190-4ec9-9105-c9ee80b7a96f
Source identifiers:
606906
Local pid:
pubs:606906

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