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Microarray-based ultra-high resolution discovery of genomic deletion mutations.

Abstract:

BACKGROUND: Oligonucleotide microarray-based comparative genomic hybridization (CGH) offers an attractive possible route for the rapid and cost-effective genome-wide discovery of deletion mutations. CGH typically involves comparison of the hybridization intensities of genomic DNA samples with microarray chip representations of entire genomes, and has widespread potential application in experimental research and medical diagnostics. However, the power to detect small deletions is low. RESULTS:...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/1471-2164-15-224

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Institution:
University of Oxford
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Institution:
University of Oxford
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Institution:
University of Oxford
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Institution:
University of Oxford
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Institution:
University of Oxford
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Publisher:
BioMed Central Ltd. Publisher's website
Journal:
BMC genomics Journal website
Volume:
15
Issue:
1
Pages:
224
Publication date:
2014-01-05
DOI:
EISSN:
1471-2164
ISSN:
1471-2164
URN:
uuid:45f00528-43b3-45d8-95ce-fdedd1a4017b
Source identifiers:
458682
Local pid:
pubs:458682

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